--- title: 'Conferences>$section>$unit>FoodRisk' separator: verticalSeparator: theme: moon revealOptions: transition: 'convex' backgroundTransition: 'fade' viewDistance: 5 center: false overview: true touch: true progress: true controls: true controlsTutorial: true controlsLayout: 'bottom-right' help: true mouseWheel: true slideNumber: 'c/t' autoSlide: 15000 width: '102%' height: '102%' margin: 0 minScale: 1.000000e-01 maxScale: 3 display: 'block' transitionSpeed: 'default' --- ___ ## The fate of food packaging substances : cross-contaminations,… a main challenge for the 21st century. ### Olivier Vitrac (INRAe) ___ version: production (0.25) date: January 29, 2020 content: 60 slides class: Conferences>$section>$unit>FoodRisk title: The fate of food packaging substances : cross-contaminations,… a main challenge for the 21st century. source: Vitrac_FoodRisk.pptx hash: contact: olivier.vitrac@agroparistech.fr note: ##### [17:37:58 - 29/01/2020]olivi@LX-Olivier2019> pptx2reveal_v2 with the following parameters: | **parameter** | **value** | | --------------: | -------- | | `wwwroot`: | ` /home/olivi/Bulk/fitness2019/external/output/www` | | `wwwrel`: | ` FoodRisk/Conferences` | | `wwwlib`: | ` src` | | `pptxfolder`: | ` /home/olivi/Bulk/fitness2019/external/source/conferences/FoodRisk` | | `pptx`: | ` Vitrac_FoodRisk.pptx` | | `imfolder`: | ` src_FoodRisk` | | `imsourcefolder`: | ` Vitrac_FoodRisk` | | `impat`: | ` Slide*.jpg` | | `svgpat`: | ` Slide*.svg` | | `author`: | ` Olivier Vitrac (INRAe)` | | `contact`: | ` olivier.vitrac@agroparistech.fr` | | `YAMLtitle`: | ` Conferences>$section>$unit>FoodRisk` | | `title`: | ` The fate of food packaging substances : cross-contaminations,… a main challenge for the 21st century.` | | `vrsn`: | ` 0.25` | | `mdfile`: | ` FoodRisk.md` | | `projectname`: | ` FoodRisk` | | `theme`: | ` moon` | | `resize`: | ` 1200x675` | | `initialscale`: | ` 0.8` | | `maximumscale`: | ` 2` | | `userscalable`: | ` yes` | | `headingshift`: | ` ` | | `headingshiftnotes`: | ` ##` | | `fontsize`: | ` 0.7` | | `hash`: | ` ` | | `maxtitle`: | ` 120` | | `maxcontentslide`: | ` 12` | | `favicon`: | ` ~/Bulk/fitness2019/template/favicon/favicon.ico` | | `mainindex`: | ` ` | | `dependencymain`: | ` index.html` | | `imformatpreferred`: | ` svg` | | `svgmaxsize`: | ` 1024 KB` | | `pdf`: | ` Vitrac_FoodRisk.pdf` | --- # CONTENT --- * [1/60] [The fate of food packaging substances: cross-contaminations, migrations, etc. a main challenge for the 21 st century](#/1) * [2/60] [Https://www.youtube.com/watch?v=azcnza1xhsk](#/2) * [3/60] [Slide 03/60](#/3) * [4/60] [Turn into constructive controversy](#/4) * [5/60] [1950](#/5) * [6/60] [Of](#/6) * [7/60] [C ontamination with contact](#/7) * [8/60] [The conventional description of migration](#/8) * [9/60] [The kinetics of migration depends on the diffusivity of the sustance 9](#/9) * [10/60] [The conventional description of migration](#/10) * [11/60] [Food inertia: a long history](#/11) * [12/60] [Google trends / bisphenol a: (worldwide)](#/12) --- # CONTENT (Cont'ed) --- * [13/60] [2003](#/13) * [14/60] [Badge,bpa](#/14) * [15/60] [Name of chairman](#/15) * [16/60] [But what about food packaging](#/16) * [17/60] ["it is incredible that such defenseless beings as babies should face such serious risks in a product as widely used as [...]](#/17) * [18/60] [Slide 18/60](#/18) * [19/60] [Https://EC.europa.EU/food/safety/chemical_safety/food_contact_materials_en](#/19) * [20/60] [1](#/20) * [21/60] [Specific rules for plastics](#/21) * [22/60] [New contaminants](#/22) * [23/60] [Bulky, unnecessary, hazardous packaging](#/23) * [24/60] [Vs](#/24) --- # CONTENT (Cont'ed) --- * [25/60] [Efsa has issued upward of 140 positive scientific opinions on the safety of processes to recycle plastics for use in food [...]](#/25) * [26/60] [Misuse issues (post-use contaminations) of - polyethylene terephthalate (pet)](#/26) * [27/60] [Within monolayer materials - rule of ttc (total threshold of concern)](#/27) * [28/60] [Circularity by design by recycling by alternative feedstocks](#/28) * [29/60] [Current researches](#/29) * [30/60] [Food research international 2017, 88, part a, 91-104. 30](#/30) * [31/60] [Detailed coarse](#/31) * [32/60] [Ind. eng. chem. res.](#/32) * [33/60] [Prediction of partition coefficients (nias, water) 33](#/33) * [34/60] [C ontamination without contact](#/34) * [35/60] [Packaging substances](#/35) * [36/60] [The cascade of risk assessment and management](#/36) --- # CONTENT (Cont'ed) --- * [37/60] [Https:// outgassing.nasa.gov /](#/37) * [38/60] [Manufacturing date](#/38) * [39/60] [Contamination trough the gas phase](#/39) * [40/60] [Contamination trough the gas phase](#/40) * [41/60] [>> FMECAkairp acetophenone](#/41) * [42/60] [Cross-contamination in biotechnological applications](#/42) * [43/60] [Cross-contamination in biotechnological applications](#/43) * [44/60] [Cross-contamination in biotechnological applications](#/44) * [45/60] [P reventive approaches](#/45) * [46/60] [Risk management requires the full cooperation of the supply chain](#/46) * [47/60] [Most of the packaging systems are composite](#/47) * [48/60] [Developing the cooperation along the supply chain](#/48) --- # CONTENT (Cont'ed) --- * [49/60] [Regulation EC 2023/2006](#/49) * [50/60] [Slide 50/60](#/50) * [51/60] [Chained steps: where is the critical step?](#/51) * [52/60] [Chained steps](#/52) * [53/60] [Assessing the severity of a single step](#/53) * [54/60] [Comparing the severity of several steps, packaging designs, substances](#/54) * [55/60] [Failure mode effects and - criticality analysis](#/55) * [56/60] [Paris smart city 2050 vincent callebaut architectures, 2015](#/56) * [57/60] [Strong community spirit (sustainable, safety and quality)](#/57) * [58/60] [+poor design and gmp +weak regulation rules +poor training](#/58) * [59/60] [Http://modmol.agroparistech.fr/mastereu2017/](#/59) * [60/60] [Http://fitness.agroparistech.fr](#/60) # The fate of food packaging substances: cross-contaminations, migrations, etc. a main challenge for the 21 st century ![Slide1.svg](./src_FoodRisk/Slide1.svg "slide 1 of 60") note: ### The fate of food packaging substances: cross-contaminations, migrations, etc. a main challenge for the 21 st century Olivier Vitrac, olivier.vitrac@agroparistech.fr University of Paris- Saclay, INRAe, AgroParisTech UMR 0782 SayFood “ Food Processing and - Engineering of Paris- Saclay ” UMT SafeMat “ Safe Food Contact Materials ” between AgroParisTech / INRAe and LNE 1 rue des Olympiades, 91300 Massy, France Nîmes Jan 30-31, 2020 --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 01/60 | 2825 | 3 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Diapositive de titre - Version 1 | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # https://www.youtube.com/watch?v=aZcNza1xHSk ![Slide2.svg](./src_FoodRisk/Slide2.svg "slide 2 of 60") note: ### https://www.youtube.com/watch?v=aZcNza1xHSk 1964 La malbouffe et les additifs, progrès ou danger pour le futur? Archive INA --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 02/60 | 2836 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # slide 03/60 ![Slide3.svg](./src_FoodRisk/Slide3.svg "slide 3 of 60") note: --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 03/60 | 2842 | 0 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Turn into constructive controversy ![Slide4.svg](./src_FoodRisk/Slide4.svg "slide 4 of 60") note: ### Turn into constructive controversy “Truth in science can be defined as the working hypothesis best suited to open the way to the next better one.” — Konrad Lorenz, Austria https://fitness.agroparistech.fr /fitness/external/IHEST --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 04/60 | 2864 | 3 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Diapositive de titre - Version 2 | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # 1950 ![Slide5.svg](./src_FoodRisk/Slide5.svg "slide 5 of 60") note: ### 1950 1980 1990 2000 Protective, active, intelligent, useful packaging --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 05/60 | 2870 | 5 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # of ![Slide6.svg](./src_FoodRisk/Slide6.svg "slide 6 of 60") note: ### Workshop “Predicting the safety of food contact articles” - New science and digital opportunities 4 October 2018, Zurich, Switzerland https://www.foodpackagingforum.org/events/predicting-the-safety-of-food-contact-articles-new-science-and-digital-opportunities Safety of food contact materials --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 06/60 | 2890 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # C ontamination with contact ![Slide7.svg](./src_FoodRisk/Slide7.svg "slide 7 of 60") note: ### C ontamination with contact = migration o ld routes = new issues « Ce grand homme à mon avis mérite d’être préféré à tous les autres… il a établi une doctrine fondée sur des raisons physiques et palpables sans se servir des énigmes inintelligibles qui font tourner la tête plutôt que d’instruire » François-Marie-Pompée Colonna – Abrégé de la doctrine de Paracelse et de ses - Archidoxes - Paris, 1724 . --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 07/60 | 2937 | 4 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Diapositive de titre - Version 1 | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # The conventional description of migration ![Slide8.svg](./src_FoodRisk/Slide8.svg "slide 8 of 60") note: ### The conventional description of migration - Observational evidences --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 08/60 | 2946 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Page classique | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # The kinetics of migration depends on the diffusivity of the sustance 9 ![Slide9.svg](./src_FoodRisk/Slide9.svg "slide 9 of 60") note: ### The kinetics of migration depends on the diffusivity of the sustance 9 --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 09/60 | 2952 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | 1_Titre seul | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # The conventional description of migration ![Slide10.svg](./src_FoodRisk/Slide10.svg "slide 10 of 60") note: ### The conventional description of migration - The level of contamination depends essentially on the fatty character of the food in contact 1/50 50 1/50 50 more chemical affinity for P more chemical affinity for F --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 10/60 | 2959 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Page classique | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Food inertia: a long history ![Slide11.svg](./src_FoodRisk/Slide11.svg "slide 11 of 60") note: ### Food inertia: a long history - Le règlement de 1908: « …aucune substance alimentaire ne doit contenir de produit nuisible, produit chimiques… » --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 11/60 | 2965 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | 1_Titre et contenu | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Google Trends / Bisphenol A: (Worldwide) ![Slide12.svg](./src_FoodRisk/Slide12.svg "slide 12 of 60") note: ### Google Trends / Bisphenol A: (Worldwide) CANCO : Ensuring the safety of consumers : can coatings for direct food contact. Project QLAM-2001-00066. Current Biology 2003, 13, 546 LOI no 2012-1442 du 24 décembre 2012 Current Biology 2018, 28,1 REGULATION 2018/213/EC --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 12/60 | 2977 | 6 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # 2003 ![Slide13.jpg](./src_FoodRisk/Slide13.jpg "slide 13 of 60") note: ### 2003 2018 --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 13/60 | 3030 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # BADGE,BPA ![Slide14.svg](./src_FoodRisk/Slide14.svg "slide 14 of 60") note: ### BADGE,BPA benzophenones diisocyanate ITX MOA biocides --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 14/60 | 3038 | 6 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Name of chairman ![Slide15.svg](./src_FoodRisk/Slide15.svg "slide 15 of 60") note: ### Name of chairman Food and Feed borne crises throughout the food chain - Bovine Spongiform Encephalopathy B S E Dioxins Mycotoxins Chloramphenicol CAP Sudan red destroy consumer‘s confidence in food NESTLE SLIDES PRESENTED DURING ILSI2004 (BARCELONA) --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 15/60 | 3057 | 9 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # But what about food packaging ![Slide16.svg](./src_FoodRisk/Slide16.svg "slide 16 of 60") note: ### But what about food packaging? Semicarbazide/SEM Organic solvents/ residues - Bisphenol A diglycidyl ether (BADGE) Nonylphenol NP NESTLE SLIDES PRESENTED DURING ILSI2004 (BARCELONA) --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 16/60 | 3082 | 7 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # "It is incredible that such defenseless beings as babies should face such serious risks in a product as widely used as [...] ![Slide17.svg](./src_FoodRisk/Slide17.svg "slide 17 of 60") note: ### "It is incredible that such defenseless beings as babies should face such serious risks in a product as widely used as milk" --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 17/60 | 3111 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # slide 18/60 ![Slide18.svg](./src_FoodRisk/Slide18.svg "slide 18 of 60") note: --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 18/60 | 3122 | 0 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # https://EC.europa.EU/food/safety/chemical_safety/food_contact_materials_en ![Slide19.svg](./src_FoodRisk/Slide19.svg "slide 19 of 60") note: ### https://EC.europa.EU/food/safety/chemical_safety/food_contact_materials_en --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 19/60 | 3128 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Titre seul | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # 1 ![Slide20.svg](./src_FoodRisk/Slide20.svg "slide 20 of 60") note: ### Contradictions and risk scale Plastics Printing inks Adhesives Solvents, polymerization aids - Biocides Coatings Paper and board --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 20/60 | 3153 | 8 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # SPECIFIC RULES FOR PLASTICS ![Slide21.svg](./src_FoodRisk/Slide21.svg "slide 21 of 60") note: ### SPECIFIC RULES FOR PLASTICS EU regulation 10/2011/EC https://www.plasticseurope.org/application/files/2615/2933/0926/The_Role_of_Food_Packaging_2018.pdf --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 21/60 | 3214 | 3 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | 1_Deux contenus | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # New contaminants ![Slide22.jpg](./src_FoodRisk/Slide22.jpg "slide 22 of 60") note: ### New contaminants =Non Intentionally Added Substances Packaging have been used for long before thinking about the consequences --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 22/60 | 3222 | 3 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Diapositive de titre - Version 1 | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Bulky, unnecessary, hazardous packaging ![Slide23.svg](./src_FoodRisk/Slide23.svg "slide 23 of 60") note: ### Bulky, unnecessary, hazardous packaging --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 23/60 | 3231 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | 1_Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # vs ![Slide24.svg](./src_FoodRisk/Slide24.svg "slide 24 of 60") note: ### vs --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 24/60 | 3238 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # EFSA has issued upward of 140 positive scientific opinions on the safety of processes to recycle plastics for use in food [...] ![Slide25.svg](./src_FoodRisk/Slide25.svg "slide 25 of 60") note: ### EFSA has issued upward of 140 positive scientific opinions on the safety of processes to recycle plastics for use in food contact material. ONLY recycled PET is authorized in EU. 500 M€ have been invested in plants capable of converting recycled plastic materials into materials suitable for packaging and food contact applications In 2014, more than 50% of the recycled PET in Europe was used in food contact applications . The lack of harmonisation amongst Member States generates legal uncertainty and unnecessary burden for the industry using recycled materials. It also sets up obstacles for the - Circular Economy FOOD GRADE GARBAGE (POST-CONSUMER MATERIALS) COLLECTION WITH NON- FOOD GRADE MATERIALS SUPER CLEANING IS THE RECYCLED MATERIAL AS SAFE AS THE ORIGINAL ONE? POSSIBLE MISS-USE FILLING WITH FOOD AGAIN Recycling plastics for food contact REGULATION 282/2008/EC --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 25/60 | 3261 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Misuse issues (post-use contaminations) of - Polyethylene terephthalate (PET) ![Slide26.svg](./src_FoodRisk/Slide26.svg "slide 26 of 60") note: ### Misuse issues (post-use contaminations) of Polyethylene terephthalate (PET) can be easily handled: glassy polymer, it is mainly contaminated by small contaminants which can be removed by a devolatilization step above Polyolefins are rubber polymers which can be easily contaminated by high molecular weight contaminants after use. Paper and board contains large amount of residues from printing inks: aromatic (carcinogenic) and aliphatic mineral oils can be transferred without contact and lead to cross-contamination between materials J. of Chromatography A. 2013; 1293:107-19. Recycled PET for food contact is authorized (282/2008/EC) Recycled polyolefins are authorized only in - Germany Recycled paper and boards is source of recurring crises in EU. Recycling of PET vs other materials --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 26/60 | 3298 | 6 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Within monolayer materials - Rule of TTC (Total Threshold of Concern) ![Slide27.svg](./src_FoodRisk/Slide27.svg "slide 27 of 60") note: ### Within monolayer materials Rule of TTC (Total Threshold of Concern) Behind a functional barrier rule of 10 ppb for non-carcinogenic, non-mutagenic, non-reprotoxic How to used recycled recycled materials - Within multilayer and/or multimaterial No-clear guidance, specific rules case-by-case --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 27/60 | 3316 | 4 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | 1_Titre seul | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Circularity by design by recycling by alternative feedstocks ![Slide28.svg](./src_FoodRisk/Slide28.svg "slide 28 of 60") note: ### Circularity by design by recycling by alternative feedstocks --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 28/60 | 3325 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Title and Content | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Current researches ![Slide29.svg](./src_FoodRisk/Slide29.svg "slide 29 of 60") note: ### Current researches * MATERIAL DESIGN Longer lifetime Decrease material usage Improve sorting, separation, recyclability Trigger biodegradability ARTICLE DESIGN Design for dismantling Decrease material usage Digital design for reuse Digital development of biobased RECYCLING Mechanical Chemical Thermal and thermomechanical Multimaterial, multilayer FEEDSTOCKS Plastic waste based - Food waste based CO/CO 2 based --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 29/60 | 3329 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Title and Content | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Food Research International 2017, 88, Part A, 91-104. 30 ![Slide30.svg](./src_FoodRisk/Slide30.svg "slide 30 of 60") note: ### Food Research International 2017, 88, Part A, 91-104. 30 --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 30/60 | 3336 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # detailed coarse ![Slide31.jpg](./src_FoodRisk/Slide31.jpg "slide 31 of 60") note: ### TRANSPORT diffusion coefficients and their activation THERMODYNAMICS chemical affinity (Flory-type isotherms) Worst-case approaches (arbitrary) For compliance testing (Piringer’s equation) Group contribution methods (fitting) Decision tree UNIQUAC, UNIFAC, Flory—Huggins Theory from first principles (statistical physics) Free-volume theory (Vrentas-Duda) Self-association theory Full atomistic simulation or coarse-grained (no assumptions) for THERMODYNAMICS chemical affinity (Flory-type isotherms) Worst-case approaches (arbitrary) For compliance testing (Piringer’s equation) Group contribution methods (fitting) Decision tree UNIQUAC, UNIFAC, Flory—Huggins Theory from first principles (statistical physics) Free-volume theory (Vrentas-Duda) Self-association theory Full atomistic simulation or coarse-grained (no assumptions) detailed coarse 11 to 13 parameters restricted to small and rigid solutes (solvents) few polymers documented Tailored calculations Journal of Chemical Physics . 2010; 132:194902. Journal of Applied Polymer Science. 2006; 101:2167-86. Food Additives and Contaminants. 2005; 22:73-90. JRC Scientific and Technical Reports EUR 27529 EN. Ispra (Italy): European Commission; 2015. European Polymer Journal. 1998; 34:797-803. Kontogeorgis & Folas . Thermodynamic Models for Industrial Applications: From Classical and Advanced Mixing Rules to Association Theories: Wiley; 2009. Industrial & Engineering Chemistry Research. 2010; 49:7263-80. Prausnitz, Lichtenthaler & de - Azevedo . Molecular Thermodynamics of Fluid-Phase Equilibria: Pearson Education; 1998. 31 --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 31/60 | 3341 | 12 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Ind. Eng. Chem. Res. ![Slide32.svg](./src_FoodRisk/Slide32.svg "slide 32 of 60") note: ### Ind. Eng. Chem. Res. 2010, 49 (16), 7263-7280. Food Additives and Contaminants, 2009, 26 (12), 1556-1573. Molecular modeling challenged the choice of food simulants 32 Directive 2007/19/EC Missing margin of safety - Ethanol content --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 32/60 | 3362 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | 1_Titre seul | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Prediction of partition coefficients (NIAS, water) 33 ![Slide33.svg](./src_FoodRisk/Slide33.svg "slide 33 of 60") note: ### Prediction of partition coefficients (NIAS, water) 33 Industrial & Engineering Chemistry Research 2009, 48 (11), 5285-5301. International Journal of - Chemical Reactor Engineering 2010, 8. Industrial & Engineering Chemistry Research 2010, 49 (16), 7263-7280. Industrial & Engineering Chemistry Research 2017, 56 (3), 774–787. --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 33/60 | 3384 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | 1_Titre seul | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # C ontamination without contact ![Slide34.svg](./src_FoodRisk/Slide34.svg "slide 34 of 60") note: ### C ontamination without contact Cross-contamination=M ain of NIAS and new (old) routes of contamination o ld routes = new issues --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 34/60 | 3392 | 3 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Diapositive de titre - Version 1 | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Packaging substances ![Slide35.svg](./src_FoodRisk/Slide35.svg "slide 35 of 60") note: ### Packaging substances Hazard Analysis vs Risk assessment Hazard = health - Risk = occurrence --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 35/60 | 3399 | 3 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Page classique | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # The cascade of risk assessment and management ![Slide36.svg](./src_FoodRisk/Slide36.svg "slide 36 of 60") note: ### The cascade of risk assessment and management Chronic exposure Human exposome Risk Tradeoff Risk balancing Conflicts Scientific risk assessment Conflict: evaluative cognitive, evaluative, normative - Routine Conflict: cognitive Targets: Targets:DG SANCO, industry stakeholders Target: industry Target: professional associations Discourse: internal Discourse: cognitive Discourse: reflective Discourse: participatory Outcome: simple Outcome: complex Outcome: uncertain Outcome: ambiguous --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 36/60 | 3409 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Page classique | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # https:// outgassing.nasa.gov / ![Slide37.svg](./src_FoodRisk/Slide37.svg "slide 37 of 60") note: ### https:// outgassing.nasa.gov / http:// esmat.esa.int /services/outgassing_data/outgassing_data.html OUTGASSING DATA NASA and ESA maintain lists of materials with low-outgassing properties suitable for use in spacecraft, as outgassing products can condense onto optical elements, thermal radiators, or solar cells and obscure them. Materials not normally considered absorbent can release enough light-weight molecules to interfere with industrial or scientific vacuum processes. Moisture, sealants, lubricants, and adhesives are the most common sources, but even metals and glasses can release gases from cracks or impurities. --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 37/60 | 3422 | 4 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | 1_Comparaison | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Manufacturing date ![Slide38.svg](./src_FoodRisk/Slide38.svg "slide 38 of 60") note: ### Manufacturing date Unknown Sampling from local German market 04/2010 08/2010 Analysis of 2 nd sample 08/2011 Analysis of 3 rd sample Biedermann et al. (2013) 119 dry food products (3 samples/category) 1 st analysis Request of BfR 4 months 12 months Contact time  Paper and board = prevalent source of chemical contaminants in food - Mineral Oils, Printing inks, adhesives --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 38/60 | 3431 | 14 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # CONTAMINATION TROUGH THE GAS PHASE ![Slide39.svg](./src_FoodRisk/Slide39.svg "slide 39 of 60") note: ### CONTAMINATION TROUGH THE GAS PHASE TENAX packed within a 50 µm thick BOPP bag and exposed to a cardboard material formulated with 15 surrogates Experimental results at 60°C, i =1…15 Detailed modeling with FMECAengine Simplified modeling Solute independent i = 1..15 solutes at any temperature simplified at any temperature Surrogates (i) Decane (C10) Tetradecane (C14) Hexadecane (C16) Octadecane (C18) Eicosane (C20) Tetracosane (C24) Octacosane (C28) Dibutyl phthalate (DBP) Bis (2-ethylhexyl) phthalate (DEHP) Benzylbutyl phthalate (BBP) Benzophenone 4-methyl benzophenone (MBP4) Isopropyl-9H-thioxanthen-9-one Anthracene Naphthalene Food Additives and Contaminants. 2017; 34:1703-20. Freeform 13 Card - board - Freeform 15 Air Freeform 17 PP Air Freeform 21 Tenax --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 39/60 | 3467 | 8 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Page classique | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # CONTAMINATION TROUGH THE GAS PHASE ![Slide40.svg](./src_FoodRisk/Slide40.svg "slide 40 of 60") note: ### CONTAMINATION TROUGH THE GAS PHASE TENAX packed within a 50 µm thick BOPP bag and exposed to a cardboard material formulated with 15 surrogates - Food Additives and Contaminants. 2017; 34:1703-20. Migration rate --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 40/60 | 3498 | 3 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Page classique | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # >> FMECAKairP acetophenone ![Slide41.svg](./src_FoodRisk/Slide41.svg "slide 41 of 60") note: ### >> FMECAKairP acetophenone LOAD_CHEMSPIDER extraction of ChemSpiderID =7132 (' acetophenone ') completed in 10.26 s LOAD_CHEMISPIDER: updated cache 7132.mat 21-sept.-2015 21:37:19 77.6 kBytes C:\Data\Olivier\INRA\Codes\MS\cache.ChemSpider CHEMSPIDER reuses cached data for ' acetophenone ' (date=21-sept.-2015 21:37:19) ans = 9.1995e-06 >> FMECAKairP ethylbenzene LOAD_CHEMSPIDER extraction of ChemSpiderID =7219 ('ethylbenzene') completed in 11.9 s LOAD_CHEMISPIDER: updated cache 7219.mat 21-sept.-2015 21:42:34 107.1 kBytes C:\Data\Olivier\INRA\Codes\MS\cache.ChemSpider CHEMSPIDER reuses cached data for 'ethylbenzene' (date=21-sept.-2015 21:42:34) ans = 2.2485e-04 >> FMECAKairP 'benzoic acid' LOAD_CHEMSPIDER extraction of ChemSpiderID =238 ('benzoic acid') completed in 5.746 s LOAD_CHEMISPIDER: updated cache 238.mat 21-sept.-2015 21:45:01 41.2 kBytes C:\Data\Olivier\INRA\Codes\MS\cache.ChemSpider CHEMSPIDER reuses cached data for 'benzoic acid' (date=21-sept.-2015 21:45:01) ans = 1.3674e-08 Food Additives and - Contaminants 2017, 34 (10), 1703-1720 AIChE Journal 2013, 59, 1183-1212 https://github.com/ovitrac/FMECAengine PARTITION COEFFICIENTS WITH AIR --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 41/60 | 3514 | 3 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | 1_Titre seul | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Cross-contamination in biotechnological applications ![Slide42.jpg](./src_FoodRisk/Slide42.jpg "slide 42 of 60") note: ### Cross-contamination in biotechnological applications --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 42/60 | 3522 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Cross-contamination in biotechnological applications ![Slide43.svg](./src_FoodRisk/Slide43.svg "slide 43 of 60") note: ### Cross-contamination in biotechnological applications - Storage before use of over-packaging A (0 – 1 year) Storage of over-packaging A and bag B (t 1 : 0 – 3 years) Use of bag B with a liquid F (t 2 : 0 – 1 year) t 1 + t 2 Conc . Redistribution of contaminant within the over-packaging Cross- transfer between over-packaging and bag Cross- transfer between bag and liquid in use OUR SCOPE Nguyen P-M, Dorey S, Vitrac O. The Ubiquitous Issue of Cross-Mass Transfer: Applications to Single-Use Systems. Molecules. 2019; 24:3467. --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 43/60 | 3528 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Cross-contamination in biotechnological applications ![Slide44.svg](./src_FoodRisk/Slide44.svg "slide 44 of 60") note: ### Cross-contamination in biotechnological applications --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 44/60 | 3555 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # P reventive approaches ![Slide45.svg](./src_FoodRisk/Slide45.svg "slide 45 of 60") note: ### P reventive approaches - From preventive approaching to integrated engineering --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 45/60 | 3563 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Risk management requires the full cooperation of the supply chain ![Slide46.svg](./src_FoodRisk/Slide46.svg "slide 46 of 60") note: ### Risk management requires the full cooperation of the supply chain - How to establish the responsibility of stakeholders? --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 46/60 | 3570 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Most of the packaging systems are composite ![Slide47.svg](./src_FoodRisk/Slide47.svg "slide 47 of 60") note: ### Most of the packaging systems are composite --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 47/60 | 3574 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Developing the cooperation along the supply chain ![Slide48.svg](./src_FoodRisk/Slide48.svg "slide 48 of 60") note: ### Developing the cooperation along the supply chain --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 48/60 | 3583 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Regulation EC 2023/2006 ![Slide49.svg](./src_FoodRisk/Slide49.svg "slide 49 of 60") note: ### Regulation EC 2023/2006 - Good Manufacturing Practice for materials and articles intended to come in contact with food +VOLUNTARY APPROACHES & LOCAL ORDINANCES Our recommendations --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 49/60 | 3593 | 3 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Titre et contenu | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # slide 50/60 ![Slide50.svg](./src_FoodRisk/Slide50.svg "slide 50 of 60") note: --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 50/60 | 3603 | 0 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # CHAINED STEPS: where is the critical step? ![Slide51.svg](./src_FoodRisk/Slide51.svg "slide 51 of 60") note: Let imagine that we want to identify the critical steps involved in the contamination of a ready-to-eat Chinese soup by a photiniator used in the external printed surface. The pots are stored in stacks, filled at 80°C with a fatty soup. The soup is stored at room temperature up to several months and finally heated in the microwave oven. ### CHAINED STEPS: where is the critical step? Risk of contamination by a photoiniator in UV-curing printing ink STORAGE "BEFORE USE" HOT FILLING FATTY CONTACT MICROWAVE OVEN HEATING LONG-TERM STORAGE --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 51/60 | 3609 | 7 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Page classique | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # CHAINED STEPS ![Slide52.svg](./src_FoodRisk/Slide52.svg "slide 52 of 60") note: Let imagine that we want to identify the critical steps involved in the contamination of a ready-to-eat Chinese soup by a photiniator used in the external printed surface. The pots are stored in stacks, filled at 80°C with a fatty soup. The soup is stored at room temperature up to several months and finally heated in the microwave oven. ### CHAINED STEPS UV-curing printing ink 52 --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 52/60 | 3629 | 3 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | Page classique | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # ASSESSING THE SEVERITY OF A SINGLE STEP ![Slide53.svg](./src_FoodRisk/Slide53.svg "slide 53 of 60") note: There is another way to estimate the contribution of one step. It is to compare the concentration reached in the food after the four steps with the one achieved after the whole process when one step has been removed. ### ASSESSING THE SEVERITY OF A SINGLE STEP CASE OF "SETOFF” STEP C F Setoff (max. 100 days@25°C) HotFilling (max. 10 mi@80°C) Long-term storage (max. 200 days@25°C) Microwave oven heating (max. 5 min@100°C) Full methodology described in AIChE J. 2013, 59 (4), 1183-1212 Rectangle 26 Rectangle 26 c omparison with step removed c omparison with step alone --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 53/60 | 3654 | 9 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | 1_Titre et texte vertical | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # COMPARING THE SEVERITY OF SEVERAL STEPS, PACKAGING DESIGNS, SUBSTANCES ![Slide54.svg](./src_FoodRisk/Slide54.svg "slide 54 of 60") note: The so-obtained results are plotted on the following Paratoo chart and normalized according their acceptable amount in food. The most critical step is the storage of pots as stacks as setoff causes the redistribution of contaminants between the external part and inner layer. The full methodology has been generalized in a full Failure Mode Effects and Criticality approach enabling to compare designs and substances. ### COMPARING THE SEVERITY OF SEVERAL STEPS, PACKAGING DESIGNS, SUBSTANCES … tie layer = EVA =292 =186 (better) =115 (almost acceptable) =124 Concurrent design (criticality scale) Unacceptable when - Critical step (severity scale) Critical substance --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 54/60 | 3680 | 4 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | Thème Office | 1_Titre seul | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Failure Mode Effects and - Criticality Analysis ![Slide55.jpg](./src_FoodRisk/Slide55.jpg "slide 55 of 60") note: ### Failure Mode Effects and - Criticality Analysis --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 55/60 | 3705 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | 1_Titre seul | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # PARIS SMART CITY 2050 Vincent Callebaut Architectures, 2015 ![Slide56.svg](./src_FoodRisk/Slide56.svg "slide 56 of 60") note: ### PARIS SMART CITY 2050 Vincent Callebaut Architectures, 2015 Conclusions & Perspectives --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 56/60 | 3709 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # Strong community spirit (sustainable, safety and quality) ![Slide57.svg](./src_FoodRisk/Slide57.svg "slide 57 of 60") note: ### Strong community spirit (sustainable, safety and quality) Low agriculture commodity and food price High agriculture commodity and food price - Individualistic society (individual rights and initiatives valued) Think BIG with modeling Let’s the food engineer contributes to building the future. Credits: European Commission, JRC --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 57/60 | 3716 | 7 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # +poor design and GMP +weak regulation rules +poor training ![Slide58.svg](./src_FoodRisk/Slide58.svg "slide 58 of 60") note: ### +poor design and GMP +weak regulation rules +poor training = Risk of Contamination + Environmental impact - Towards a global solution --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 58/60 | 3738 | 3 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # http://modmol.agroparistech.fr/MasterEU2017/ ![Slide59.svg](./src_FoodRisk/Slide59.svg "slide 59 of 60") note: ### http://modmol.agroparistech.fr/MasterEU2017/ This lecture: http://modmol.agroparistech.fr/masterEU/ MY LECTURES AT MSU (MI,USA): http://www.fshn.msu.edu/events/event/Vitrac diffusion https://mediaspace.msu.edu/media/dr.+olivier+vitrac+presentsa+diffusion+coefficients+of+organic+solutes+in+polymersa/1_zz20dgt9 PARTITIONING https://mediaspace.msu.edu/media/Dr.+Olivier+Vitrac+presentsA+An+atomistic+Flory-Huggins+formulation+for+the+tailored+prediction+of+activity+and+partition+coefficients/1_uzi6h91k SAFETY MANAGEMENT: https://mediaspace.msu.edu/media/WorkshopA+Prediction+of+the+migrationA+beyond+conventional+estimates*/1_won1m7aw RISK ASSESSMENT: https://www.youtube.com/watch?v=7LMnc4czpuY --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 59/60 | 3745 | 2 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) # http://fitness.agroparistech.fr ![Slide60.svg](./src_FoodRisk/Slide60.svg "slide 60 of 60") note: ### http://fitness.agroparistech.fr --- | **name** | **id** | **number of objects** | **date PPTx (name)** | | :--------------: | :--------: | :-------------------: | :-----------------------------: | | slide 60/60 | 3754 | 1 | January 29, 2020 (Vitrac_FoodRisk.pptx) | | **slide master** | **layout** | **style** | **date of conversion (engine)** | | 1_Thème Office | Blank | | Jan 29, 2020 (extractTXTfromPPT) | content provided AS IS - [report a problem](mailto:olivier.vitrac@agroparistech.fr) --- # Thank you for your attention. --- ### Use this link to go back to the first slides * > [first slide](#/) * > [logo slide](#/1) * > [content slide](#/0/2) * > [title slide](#/2) --- #### report issues to [Olivier Vitrac](mailto:olivier.vitrac@agroparistech.fr)